Bladder Cancer
Cytology & F.I.S.H. Testing
Aid in the initial diagnosis of bladder cancer for patients presenting with hematuria, using a non-invasive, urine-based test.
Doc Lab® is at the forefront of innovation in molecular diagnostics. Our FISH test aids in the initial diagnosis of bladder cancer for patients presenting with hematuria. Using Fluorescence In Situ Hybridization, it detects abnormalities in chromosomes 3, 7, and 17 and loss of the 9p21 locus.
Why F.I.S.H. Matters
Hematuria is one of the most common presentations in urology, and one of the most consequential to evaluate: it can be the first visible sign of bladder cancer. Getting from symptom to answer quickly matters for every patient in that position.
Cytology and F.I.S.H. together bring cellular and chromosomal analysis to that evaluation from a simple urine specimen—no invasive collection required. Early detection of potential bladder cancer in patients presenting with hematuria, across all age groups, leads to increased survival rates.
How F.I.S.H. Works
Our dual-approach methodology combines cytology and FISH analysis. Cytology provides microscopic examination of cells—evaluating cell structure and characteristics and detecting cellular abnormalities. FISH analysis uses fluorescent probes that target specific DNA sequences, visualizing chromosomal changes and identifying genetic markers.
Behind both sits the technical foundation: state-of-the-art imaging systems, advanced molecular testing platforms, comprehensive quality control measures, and detailed, clinically relevant reporting.
The clinical benefits span the care pathway: accurate diagnosis and staging, informed treatment decisions, monitoring of treatment effectiveness, early detection of recurrence, and improved patient outcomes.
Key Benefits
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Enhanced Accuracy
FDA approved and meets all rigorous qualifications for clinical utility and validity.
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Faster Turnaround Times
Faster turnaround compared to traditional testing methods.
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Easy Collection
Non-invasive, urine specimen. No uncomfortable collection procedures for your patients.
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Comprehensive Analysis
Detailed cellular and chromosomal examination from a single specimen.
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Treatment Guidance
Inform targeted therapy decisions with clinically relevant reporting.
Test Specifications
| Test Name | Cytology & F.I.S.H. (Fluorescence In Situ Hybridization) |
|---|---|
| Methodology | Dual approach: cytology plus FISH with fluorescent probes for chromosomes 3, 7, and 17 and the 9p21 locus |
| Specimen Type | Urine (non-invasive) |
| Collection Requirements | Standard urine collection |
| Clinical Use | Aid in initial diagnosis of bladder cancer in patients presenting with hematuria |
Let's talk
Advanced Bladder Cancer Testing for Hematuria Patients
Let's discuss adding Cytology & F.I.S.H. testing to your menu for patients presenting with hematuria.